Results 41 to 50 of about 150,601 (174)
Spermine oxidase: A promising therapeutic target for neurodegeneration in diabetic retinopathy. [PDF]
Pharmacol Res, 2019 Diabetic Retinopathy (DR), is a significant public health issue and the leading cause of blindness in working-aged adults worldwide. The vision loss associated with DR affects patients' quality of life and has negative social and psychological effects. In the past, diabetic retinopathy was considered as a vascular disease; however, it is now recognized
Narayanan SP, Shosha E, D Palani C.
europepmc +4 more sources
A plant spermine oxidase/dehydrogenase regulated by the proteasome and polyamines [PDF]
Journal of Experimental Botany, 2014 Polyamine oxidases (PAOs) are flavin-dependent enzymes involved in polyamine catabolism. In Arabidopsis five PAO genes (AtPAO1-AtPAO5) have been identified which present some common characteristics, but also important differences in primary structure, substrate specificity, subcellular localization, and tissue-specific expression pattern, differences ...
Ahou, A. +12 more
openaire +5 more sources
ASSOCIATION OF SPERMINE AND DIAMINE OXIDASE ACTIVITY WITH HUMAN SPERMATOZOA [PDF]
Reproduction, 1975 Summary. Human spermatozoa, separated from the seminal plasma, contained substantial amounts of spermine, and also a distinct diamine oxidase (EC 1.4.3.6) activity. Spermine, but not diamine oxidase activity, could be removed from the spermatozoa by washing the cells with buffers containing high concentrations of salts.
P, Pulkkinen +3 more
openaire +2 more sources
Journal of Agricultural Sciences, 2022 The relationship between hydrogen peroxide and the metabolism of polyamines and the role of NADPH oxidase (NOX) in that relationship under drought conditions remains unclear.
Aykut Sağlam +3 more
doaj +1 more source
, 2010 Spermine oxidase (SMO) and acetylpolyamine oxidase (APAO) are FAD-dependent enzymes that are involved in the highly regulated pathways of polyamine biosynthesis and degradation.
Rodolfo Federico +15 more
core +3 more sources
Frontiers in Pharmacology, 2020 Non-small cell lung cancer (NSCLC) is the most lethal and prevalent type of lung cancer. In almost all types of cancer, the levels of polyamines (putrescine, spermidine, and spermine) are increased, playing a pivotal role in tumor proliferation ...
Freddy López-Contreras +9 more
doaj +1 more source
The immunological effects of the polyamine oxidase enzyme partially cleared from the cerebrospinal fluid against secondary secondary cystitis in white mice. Coagulation factor and delayed hypersensitivity [PDF]
مجلة التربية والعلم, 2007 The study included immune response to infection with secondary hydatid disease in BALB/c mice activated by partially purified cerebrospinal fluid-polyamine oxidase (CSF-PAO) with spermine and infected with protoscoleces of Echinococcus granulosus.
Khawla Al-Flaeh, Asmaa Ali, Wathba Ali
doaj +1 more source
Pathological changes in platelet histamine oxidases in atopic eczema
Mediators of Inflammation, 1993 Increased plasma histamine levels were associated with significantly lowered diamine and type B monoamine oxidase activities in platelet-rich plasma of atopic eczema (AE) patients.
Reinhold Kiehl, Gruia Ionescu
doaj +1 more source
Cells, 2022 Cell detachment techniques using animal-derived enzymes are necessary for the production of biopharmaceuticals that are made with the help of adherent cell cultures, although the majority of protein therapeutics (>USD 100 billion of income per year) are ...
Shouzhi Yu +10 more
doaj +1 more source
Alterations of renal polyamine metabolism in mice with folic acid-induced chronic kidney disease
Biochemistry and Biophysics ReportsChronic kidney disease (CKD) often follows acute kidney injury, leading to renal fibrosis and progressive renal failure. Spermine, a polyamine with antioxidant and anti-inflammatory properties, helps reduce renal fibrosis and may serve as a biomarker for
Cheng Xue +4 more
doaj +1 more source