Results 31 to 40 of about 2,808,407 (277)

IP(3) receptor subtype-dependent activation of store-operated calcium entry through I(CRAC). [PDF]

, 2009
The store-operated, calcium release-activated calcium current I(CRAC) is activated by the depletion of inositol 1,4,5-trisphosphate (IP(3))-sensitive stores.
Penner, Reinhold, Fleig, Andrea, Peinelt, Christine, Beck, Andreas, Monteilh-Zoller, Mahealani K   +4 more
core   +4 more sources

The heterogeneity of store-operated calcium entry in melanoma [PDF]

Science China Life Sciences, 2016
Calcium is a key regulator of many physiological processes that are perturbed in cancer, such as migration, proliferation and apoptosis. The proteins STIM and Orai mediate store-operated calcium entry (SOCE), the main pathway for calcium entry in non-excitable cells.
Hooper, Robert, Zaidi, M. Raza, Soboloff, Jonathan   +2 more
openaire   +2 more sources

Junctate is a key element in calcium entry induced by activation of InsP3 receptors and/or calcium store depletion [PDF]

, 2004
In many cell types agonist-receptor activation leads to a rapid and transient release of Ca(2+) from intracellular stores via activation of inositol 1,4,5 trisphosphate (InsP(3)) receptors (InsP(3)Rs).
Arnoult, Christophe, Cristiano Grasso, Treves, Susan, Ronjat, Michel, Mikoshiba, Katsuhiko, ARNOULT C, GRASSO C, TREVES, Susan Nella, Ducreux, Sylvie, DUCREUX S, Smida-Rezgui, Sophia, Franzini-Armstrong, Clara, MIKOSHIBA K, SCHRUM A, Sylvie Ducreux, Susan Treves, RONJAT M, Grasso, Cristiano, Zhu, Michael X., Zorzato, Francesco, SMIDA REZGUI S, Sophia Smida-Rezgui, MOCCAGATTA L, Zhu, Michael, Francesco Zorzato, Clara Franzini-Armstrong, Christophe Arnoult, Luca Moccagatta, Schrum, Adam, Michel Ronjat, ZHU MX, GIRARD T, Girard, Thierry, Katsuhiko Mikoshiba, Thierry Girard, FRANZINI ARMSTRONG C, Moccagatta, Luca, Michael X. Zhu, Adam Schrum   +38 more
core   +1 more source

Obligatory role for phosphatidylinositol 4,5-bisphosphate in activation of native TRPC1 store-operated channels in vascular myocytes [PDF]

, 2009
In the present study the effect of phosphatidylinositol 4,5-bisphosphate (PIP2) was studied on a native TRPC1 store-operated channel (SOC) in freshly dispersed rabbit portal vein myocytes.
Saleh, Sohag N., Albert, Anthony P., Large, William A., Large, WA, Saleh, SN, Albert, AP   +5 more
core   +1 more source

Activation and regulation of store‐operated calcium entry

Journal of Cellular and Molecular Medicine, 2010
Abstract Introduction I CRAC Orais STIM1 STIM2 STIM1, STIM2 and Ca2+ oscillations TRPCs and SOCE Conclusions The process of store‐operated Ca2+ entry (SOCE), whereby Ca2+ influx across the plasma membrane is activated in response to depletion of intracellular Ca2+ stores in the endoplasmic reticulum (ER), has been under investigation ...
Smyth, Jeremy T, Hwang, Sung-Yong, Tomita, Takuro, DeHaven, Wayne I, Mercer, Jason C, Putney, James W   +5 more
openaire   +3 more sources

Role of the JP45-Calsequestrin Complex on Calcium Entry in Slow Twitch Skeletal Muscles [PDF]

, 2016
We exploited a variety of mouse models to assess the roles of JP45-CASQ1 (CASQ, calsequestrin) and JP45-CASQ2 on calcium entry in slow twitch muscles.
Treves S, Treves, Susan, TREVES, Susan Nella, Protasi F, De Negri M4, Bongianino, Rossana, Bergamelli L, De Negri M, Bongianino R4, Mosca B, Priori, Silvia G., Priori SG, Zorzato, Francesco, Eckhardt J, Eckhardt, Jan, Mosca, Barbara, Bergamelli, Leda, Protasi F6, PRIORI, SILVIA GIULIANA, Zorzato F, De Negri, Marco, Eckhardt J2, Protasi, Feliciano, Bongianino R, Priori SG5   +24 more
core   +1 more source

Calcium homeostasis and cone signaling are regulated by interactions between calcium stores and plasma membrane ion channels.

PLoS ONE, 2009
Calcium is a messenger ion that controls all aspects of cone photoreceptor function, including synaptic release. The dynamic range of the cone output extends beyond the activation threshold for voltage-operated calcium entry, suggesting another calcium ...
Tamas Szikra, Peter Barabas, Theodore M Bartoletti, Wei Huang, Abram Akopian, Wallace B Thoreson, David Krizaj   +6 more
doaj   +1 more source

CaMKIIβ knockdown decreases store-operated calcium entry in hippocampal dendritic spines

IBRO Neuroscience Reports, 2022
Calcium/calmodulin-dependent protein kinase II (CaMKII) and neuronal store-operated calcium entry (nSOCE) have been implicated in the development of Alzheimer's disease (AD).
Nikita Zernov, Ilya Bezprozvanny, Elena Popugaeva   +2 more
doaj   +1 more source

Store-operated calcium entry in disease: Beyond STIM/Orai expression levels. [PDF]

, 2019
Precise intracellular calcium signaling is crucial to numerous cellular functions. In non-excitable cells, store-operated calcium entry (SOCE) is a key step in the generation of intracellular calcium signals.
Borgström, Anna, Kappel, Sven, Dörr, Kathrin, Stoklosa, Paulina, Peinelt, Christine   +4 more
core   +3 more sources

Store-Operated Calcium Entry in Skeletal Muscle: What Makes It Different?

Cells, 2021
Current knowledge on store-operated Ca2+ entry (SOCE) regarding its localization, kinetics, and regulation is mostly derived from studies performed in non-excitable cells.
Elena Lilliu, Stéphane Koenig, Xaver Koenig, Maud Frieden   +3 more
doaj   +1 more source