Results 91 to 100 of about 4,909 (142)

Advances in research on RNA methylation and cancer radiotherapy resistance

Frontiers in Oncology
RNA methylation is a type of reversible chemical modification in epitranscriptomics that influences gene expression by dynamically regulating RNA functions.
Hui Liu, Hui Luo, Ming Jin, Zhen Zheng, Yang Xi, Kaitai Liu   +5 more
doaj   +1 more source

Exploration of the prognostic value of methylation regulators related to m5C in papillary thyroid carcinoma

Medicine
The incidence of papillary thyroid carcinoma (PTC) has increased significantly in recent years, and for patients with metastatic and recurrent PTC, the options for treatment currently available are insufficient. To date, the exact molecular mechanism underlying PTC is still not fully understood. 5-Methylcytosine (m5C) RNA methylation is associated with
Furong Nie, Jiacheng Jiang, Jie Ning
openaire   +2 more sources

ALYREF m5C RNA methylation reader predicts bladder cancer prognosis by regulating the tumor immune microenvironment

Medicine
Background: 5-Methylcytidine (m5C) methylation is a recently emerging epigenetic modification that is closely related to tumor proliferation, occurrence, and metastasis. This study aimed to investigate the clinicopathological characteristics and prognostic value of m5C regulators in bladder cancer (BLCA), and their correlation ...
Wengu Pan, Xiaoli Liu, Shuangde Liu
openaire   +2 more sources

Identification of the m6A/m5C/m1A methylation modification genes in Alzheimer’s disease based on bioinformatic analysis

Aging
As a progressive neurodegenerative disease, the comprehensive understanding of the pathogenesis of Alzheimer's disease (AD) is yet to be clarified. Modifications in RNA, including m6A/m5C/m1A, affect the onset and progression of many diseases. Consequently, this study focuses on the role of methylation modification in the pathogenesis of AD.Three AD ...
Tan, Qifa, Zhou, Desheng, Guo, Yuan, Chen, Haijun, Xie, Peng   +4 more
openaire   +2 more sources

Identification and validation of novel prognostic signatures based on m5C methylation patterns and tumor EMT profiles in head and neck squamous cell carcinoma. [PDF]

Sci Rep, 2023
Zhu G, Wang W, Yao H, Li H, Zhang C, Meng Y, Wang J, Zhu M, Zheng H.   +8 more
europepmc   +1 more source

Development and Validation of a Machine Learning Prognostic Model of m5C Related immune Genes in Lung Adenocarcinoma

Cancer Control
Background The aim of this retrospective research was to develop an immune-related genes significantly associated with m5C methylation methylation (m5C-IRGs)-related signature associated with lung adenocarainoma (LUAD).
Xiong Cao, Yuxing Ji, Jiajia Li, Zhikang Liu, Chang Chen   +4 more
doaj   +1 more source

HNEAP Regulates Necroptosis of Cardiomyocytes by Suppressing the m⁵ C Methylation of Atf7 mRNA. [PDF]

Adv Sci (Weinh), 2023
Wang K, Li FH, Zhou LY, Zhao XM, Gao XQ, Liu CY, Li XM, Chen XZ, Zhao Y, Cheng XL, Wang RQ, Li RF, Zhang YH, Gao F, Tian JW, Wang K.   +15 more
europepmc   +1 more source

NSUN2-mediated M⁵c methylation of IRF3 mRNA negatively regulates type I interferon responses during various viral infections. [PDF]

Emerg Microbes Infect, 2023
Wang H, Feng J, Zeng C, Liu J, Fu Z, Wang D, Wang Y, Zhang L, Li J, Jiang A, He M, Cao Y, Yan K, Tang H, Guo D, Xu K, Zhou X, Zhou L, Lan K, Zhou Y, Chen Y.   +20 more
europepmc   +1 more source

NSUN2 promotes osteosarcoma progression by enhancing the stability of FABP5 mRNA via m⁵C methylation. [PDF]

Cell Death Dis, 2023
Yang M, Wei R, Zhang S, Hu S, Liang X, Yang Z, Zhang C, Zhang Y, Cai L, Xie Y.   +9 more
europepmc   +1 more source

Neuronal Depolarization Induced RNA m⁵C Methylation Changes in Mouse Cortical Neurons. [PDF]

Biology (Basel), 2022
Xu X, Johnson Z, Xie H.
europepmc   +1 more source