Results 131 to 140 of about 5,548 (154)

MLLT3 Regulates Melanoma Stemness and Progression by Inhibiting HMGB1 Nuclear Entry and MAGEA1 M⁵C Modification. [PDF]

Adv Sci (Weinh)
Li Y, Liu H, Li J, Fu C, Jiang B, Chen B, Zou Y, Yu B, Song B.   +8 more
europepmc   +1 more source

Corrigendum: No evidence for epitranscriptomic m⁵C modification of SARS-CoV-2, HIV, and MLV viral RNA. [PDF]

RNA
Huang A, Riepler L, Rieder D, Kimpel J, Lusser A.   +4 more
europepmc   +1 more source

NSUN2-mediated m⁵C modification drives alternative splicing reprogramming and promotes multidrug resistance in anaplastic thyroid cancer through the NSUN2/SRSF6/UAP1 signaling axis. [PDF]

Theranostics
Hou X, Dong Q, Hao J, Liu M, Ning J, Tao M, Wang Z, Guo F, Huang D, Shi X, Gao M, Li D, Zheng X.   +12 more
europepmc   +1 more source

Roles of RNA m⁵C modification patterns in prognosis and tumor microenvironment infiltration of diffuse large B-cell lymphoma. [PDF]

Am J Cancer Res
Cui W, Luo C, Zhou L, Yu T, Meng Y, Yu Q, Lei Z, Wang Y, Peng L, Luo Q, Tang D, Sun R, Yu L.   +12 more
europepmc   +1 more source

Metabolic Recoding of NSUN2-Mediated m⁵C Modification Promotes the Progression of Colorectal Cancer via the NSUN2/YBX1/m⁵C-ENO1 Positive Feedback Loop. [PDF]

Adv Sci (Weinh)
Chen B, Deng Y, Hong Y, Fan L, Zhai X, Hu H, Yin S, Chen Q, Xie X, Ren X, Zhao J, Jiang C.   +11 more
europepmc   +1 more source

m6A and m5C modifications as the gears: CmoCK1 mRNA travels to promote chilling tolerance

Plant Physiology
openaire   +2 more sources

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Emerging Role of RNA m5C Modification in Cardiovascular Diseases

Journal of Cardiovascular Translational Research, 2022
Epitranscriptomics is the emerging field of research that comprises the study of epigenetics changes in RNAs. Progressing development in the field of epigenetics has helped to manage and comprehend human diseases. RNA methylation regulates all aspects of RNA functions, which are involved in the pathogenesis of human diseases.
Kannan, Balachander, Jayaseelan Vijayashree, Priyadharsini, Anitha, Roy, Arumugam, Paramasivam   +3 more
openaire   +2 more sources

m5C-Seq: Machine learning-enhanced profiling of RNA 5-methylcytosine modifications

Computers in Biology and Medicine
Epigenetic modifications, particularly RNA methylation and histone alterations, play a crucial role in heredity, development, and disease. Among these, RNA 5-methylcytosine (m5C) is the most prevalent RNA modification in mammalian cells, essential for processes such as ribosome synthesis, translational fidelity, mRNA nuclear export, turnover, and ...
Zeeshan Abbas, Mobeen Ur Rehman, Hilal Tayara, Seung Won Lee, Kil To Chong   +4 more
openaire   +2 more sources

The Role of RNA m5C Modification in Central Nervous System Diseases

Discovery Medicine
As advances in RNA modification research progress, the significance of 5-methylcytosine (m5C) modification is being increasingly acknowledged. m5C undergoes modification by the methyltransferase NOP2/Sun domain (NSUN) family/DNA methyltransferase (DNMT) family (writer) and is removed by demethylases (eraser), including the ten-eleven translocation (TET)
Peiyan, Wu, Jiaxiang, Gao, Guangming, Lan, Yichao, Wang   +3 more
openaire   +2 more sources