Results 101 to 110 of about 2,920 (152)

NSUN2-mediated m5C modification of HIV-1 RNA enables evasion of RIG‑I‑dependent innate immunity. [PDF]

PLoS Pathog
Xu Y, Li M, Song Y, Kong W, Song J, Zhang J, Xu X, Ma H, Yu S, Chen S, Zeng C.   +10 more
europepmc   +1 more source

The tRNA methylation activity and specificity of NSUN2 are independent of Archease

Transfer RNAs (tRNAs) undergo extensive maturation, including modifications essential for translation efficiency and fidelity, as well as for structural stability. The modification cytosine-5 methylation (m 5 C) is
Elisa Vilardo, Maria Waldl, Moritz Kleinwächter, Javier Martinez, Valentina Stuchlik, Ivo L. Hofacker, Fatinah El-Isa, Anna Rocchegiani, Alexandra Lusser, Anming Huang   +9 more
core   +1 more source

Metabolic Reprogramming of <i>NSUN2</i>-Mediated m⁵C Modification Promotes the Progression of Hepatocellular Carcinoma by Restricting Natural Killer Cell-Mediated Cytotoxicity. [PDF]

Cancer Commun (Lond)
Mao S, Fang Y, Gao J, Chen J, Guan Z, Zhao X, Wu J, Wu X, Zhu G, Zhang X, Zhao Q, Yang R, Wang Y, Chu T, Bu Y, Fu J, Li H, Tang Z, Shi Y, Zhou J, Fan J, Jiang J, Liu W.   +22 more
europepmc   +1 more source

Shikonin promotes ferroptosis though NSUN2-mediated m5C methylation modification of TFRC in acute myelocytic leukemia

Shikonin (SHK), extracted from the traditional Chinese herb Lithospermum erythrorhizon, demonstrates a wide range of pharmacological activities.
Shuyu Chen, Yiqun Huang, Yinhao Liu, Liuxuan Jiang, Yuqing Chen   +4 more
core   +1 more source

RNA-Binding Peptide Influences Epitranscriptomic Regulation by Preferentially Binding to Unmodified RNAs Targeted by NSUN2. [PDF]

Biomolecules
Ekanayake C, Mollah A, Thompson M, Hout E, Thalagaha Mudiyanselage C, Abeysirigunawardena S.   +5 more
europepmc   +1 more source

NSUN2-Mediated m⁵C Methylation in Human Disease: Mechanism and Therapeutic Implications. [PDF]

Int J Gen Med
Zheng X, Zhao S, Gu H, Jiang P, Zheng L.
europepmc   +1 more source

m5C Methylation of mRNA: Still More Questions Than Answers. [PDF]

Cells
Babaylova ES, Zolotenkova EA, Malygin AA.   +2 more
europepmc   +1 more source

NSUN2‑mediated epitranscriptomic and ubiquitin modulation of Nipah virus matrix protein reveals a dual-targeting antiviral strategy. [PDF]

Protein Cell
Hao H, Chen Z, Zhang F, Huang Y, Luo F, Zuo L, Luo T, Wang X, Shang C, Shan C, Liu H, Zhang X, Yuan Z, Huang F, Guan W.   +14 more
europepmc   +1 more source

NSUN2-mediated m5C modification of E2F1 promotes lung adenocarcinoma progression via the RAD54L signaling axis. [PDF]

Respir Res
Li Y, Chen C, Liu H, Zhang Z, Wang C.
europepmc   +1 more source

<i>NSUN2</i> mediates <i>SALL2</i> m5C methylation to inhibit ferroptosis and promote breast cancer progression. [PDF]

Cancer Biol Ther
Li J, Li M, Guo J, Li D, Yao Y, Zhang W, Cui C, Fu B.   +7 more
europepmc   +1 more source