Results 11 to 20 of about 52,257,618 (175)
OXA-48-Like-Producing Klebsiella pneumoniae in Southern Spain in 2014-2015. [PDF]
Antimicrob Agents Chemother, 2019 The aim of this study was to characterize the population structure of 56 OXA-48-like-producing Klebsiella pneumoniae isolates, as well as extended-spectrum β-lactamase (ESBL) and carbapenemase genes, recovered in 2014 and 2015 from 16 hospitals in ...
Machuca J +6 more
europepmc +10 more sources
Journal of Global Antimicrobial Resistance, 2020 Objectives: The aim of this study was to elucidate the molecular features of genes, plasmids and clones of OXA-48-like producingKlebsiella pneumoniae isolates recovered in Sahloul Hospital (Sousse, Tunisia) in the period 2012–2014.
Aziza Messaoudi +8 more
doaj +4 more sources
Mechanistic Basis of OXA-48-like β-Lactamases' Hydrolysis of Carbapenems. [PDF]
ACS Infect Dis, 2021 Carbapenem-hydrolyzing class D β-lactamases (CHDLs) are an important source of resistance to these last resort β-lactam antibiotics. OXA-48 is a member of a group of CHDLs named OXA-48-like enzymes. On the basis of sequence similarity, OXA-163 can be classified as an OXA-48-like enzyme, but it has altered substrate specificity.
Stojanoski V +6 more
europepmc +6 more sources
Journal of Infection and Public Health, 2017 Summary: Little is known of carbapenemase producing Klebsiella pneumoniae (CPK) in Jordan. This study aimed to determine the prevalence of CPK in a major hospital in Amman, Jordan in 2012–2013 and to characterize the isolates and detect the types of ...
Amin A. Aqel +5 more
doaj +6 more sources
Heterogeneous hydrolytic features for OXA-48-like β-lactamases [PDF]
Journal of Antimicrobial Chemotherapy, 2015 Objectives: Carbapenem-hydrolysing class D β-lactamases of the OXA-48 type are increasingly reported from Enterobacteriaceae. β-Lactamase OXA-48 hydrolyses penicillins very efficiently, but carbapenems only weakly and spares broad-spectrum ...
Oueslati, Saoussen +5 more
core +8 more sources
Discovery of bla(OXA-199), a chromosome-based bla(OXA-48)-like variant, in Shewanella xiamenensis. [PDF]
PLoS ONE, 2012 INTRODUCTION: bla(OXA-48) is a globally emerging carbapenemase-encoding gene. The progenitor of bla(OXA-48) appears to be a Shewanella species. The presence of the bla(OXA-48)-like gene was investigated for two Shewanella xiamenensis strains.
Zhiyong Zong
doaj +2 more sources
First Isolates of OXA-48-Like Carbapenemase-Producing Enterobacteriaceae in A Specialized Cancer Center. [PDF]
Infect Chemother, 2022 BACKGROUND: OXA-48-like carbapenemases have been found in a growing and varied number of carbapenemase-producing Enterobacteriaceae (CPE) isolates, and they are spreading to several countries.
Villanueva-Cotrina F +4 more
europepmc +4 more sources
Emergence and Spread of OXA-48-Like Carbapenemase-Producing Enterobacteriaceae [PDF]
Korean Journal of Nosocomial Infection Control, 2015 Since 2001, ten more OXA-48 variants have been identified. Shewanella spp. has been thought to be the original host for OXA-48-like enzymes. These enzymes strongly hydrolyze penicillins and weakly hydrolyze carbapenems, with very weak activity against ...
이경원, 정석훈
core +2 more sources
OXA-48-like carbapenemases producing Enterobacteriaceae in different niches [PDF]
European Journal of Clinical Microbiology & Infectious Diseases, 2017 International audienceThe emergence of carbapenem-resistant enterobacterial species poses a serious threat to public health worldwide. OXA-48-type carbapenem-hydrolyzing class D β-lactamases are widely distributed among Enterobacteriaceae, with ...
Jean-Philippe Lavigne +9 more
core +4 more sources
OXA-484, an OXA-48-Type Carbapenem-Hydrolyzing Class D β-Lactamase From Escherichia coli
Frontiers in Microbiology, 2021 OXA-48-like carbapenemases are among the most frequent carbapenemases in Gram-negative Enterobacterales worldwide with the highest prevalence in the Middle East, North Africa and Europe.
Julian Sommer +13 more
doaj +2 more sources