Results 131 to 140 of about 1,509 (185)

The geroscience hypothesis: Economic paradigms and pharmacological strategies for healthspan extension. [PDF]

J Taibah Univ Med Sci
Alotaibi AF, Aljasser AI, Alkattan AN, Alkhoraisi A, Assiri AM.   +4 more
europepmc   +1 more source

Senescence Modulation: An Applied Science Review of Strategies in Anti-Aging, Regenerative Aesthetics, and Oncology Therapy. [PDF]

Curr Issues Mol Biol
Kusmanto SJ.
europepmc   +1 more source

Targeting Cellular Senescence to Enhance Human Endometrial Stromal Cell Decidualization and Inhibit Their Migration [PDF]

Cellular senescence leads to stable cell cycle arrest and an inflammatory senescence-associated secretory phenotype that varies with stressor and cell type. To mitigate these effects and improve health, senotherapeutics (e.g., senolytics and senomorphics)

core   +1 more source

Development of Reliable and High-Throughput Human Biomimetic Cartilage and Bone Models to Explore Senescence and Personalized Osteoarthritis Treatment Options [PDF]

To facilitate effective preclinical testing of senescence treatments for osteoarthritis (OA), we have created reliable biomimetic and high-throughput models using aged human joint tissues.
Boone, Ilja, de Keizer, Peter L.J., Houtman, Evelyn, Lehmann, Johannes, Meulenbelt, Ingrid, Nelissen, Rob G.H.H., Tuerlings, Margo, van den Berg, Jim J.   +7 more
core  

The paradox of cellular senescence in prostate cancer: from tumor suppression to tumor promotion. [PDF]

Front Oncol
Xing Y, Qin G, Lin X, Chen S, Su Y, Lin T, Chen G.   +6 more
europepmc   +1 more source

Senotherapeutics in Malignant Brain Cancer Therapy. [PDF]

Curr Oncol Rep
Kaina B, Christmann M.
europepmc   +1 more source

Nicotinamide Mononucleotide Decreases Secretion of Proinflammatory Cytokines via the NAD <b>⁺</b> /SIRT1/p65 Axis. [PDF]

ACS Omega
Zhang D, Li Z, Meng X, Wang T, Miao Z, Deng H.   +5 more
europepmc   +1 more source

Rewinding the Clock: Emerging Pharmacological Strategies for Human Anti-Aging Therapy. [PDF]

Int J Mol Sci
Delrue C, Speeckaert R, Speeckaert MM.
europepmc   +1 more source

Senescent endothelial cells: key commanders of the cellular communication network within atherosclerotic plaques. [PDF]

Front Immunol
Xie F, Xi C, Bao G, Yang B, Zheng X, Fu B, Zheng Z.   +6 more
europepmc   +1 more source

The promise of organ rejuvenation to overcome the shortage in organ transplantation. [PDF]

Nat Commun
Kayumov M, Song Z, Martin F, Tsou S, Xiao Y, Zhou H, Tullius SG.   +6 more
europepmc   +1 more source