Results 41 to 50 of about 1,543 (178)
Frontiers in Endocrinology, 2023 Recent advances in aging research have provided novel insights for the development of senotherapy, which utilizes cellular senescence as a therapeutic target.
Sachi Matsubayashi +3 more
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, 2021 Senotherapeutics are new drugs that can modulate senescence phenomena within tissues and reduce the onset of age-related pathologies. Senotherapeutics are divided into senolytics and senomorphics.
Mustafa Burak Acar (11523127) +7 more
core +1 more source
Las células senescentes como factores patogénicos y posibles dianas terapéuticas en osteoporosis [PDF]
, 2023 Cellular senescence is a process induced by various types of stress that irreversibly cause cell cycle arrest and changes to the characteristics and functionality of cells, as well as the acquisition of a secretory phenotype that generates a pro-in ...
de Blas Rodríguez, Manuela +3 more
core +1 more source
, 2021 Senotherapeutics are new drugs that can modulate senescence phenomena within tissues and reduce the onset of age-related pathologies. Senotherapeutics are divided into senolytics and senomorphics.
Mustafa Burak Acar (11523127) +7 more
core +1 more source
Maternal diabetes induces senescence and neural tube defects sensitive to the senomorphic rapamycin [PDF]
Science Advances, 2020 A microRNA-activated pathway in maternal diabetes–induced neuroepithelial cell senescence leads to neural tube defects.
Cheng Xu +6 more
openaire +3 more sources
, 2021 Senotherapeutics are new drugs that can modulate senescence phenomena within tissues and reduce the onset of age-related pathologies. Senotherapeutics are divided into senolytics and senomorphics.
Mustafa Burak Acar (11523127) +7 more
core +1 more source
, 2021 Senotherapeutics are new drugs that can modulate senescence phenomena within tissues and reduce the onset of age-related pathologies. Senotherapeutics are divided into senolytics and senomorphics.
Mustafa Burak Acar (11523127) +7 more
core +1 more source
Frontiers in Aging, 2023 Introduction: Doxorubicin (DOX), a chemotherapeutic drug, induces senescence and increases the secretion of senescence-associated secretory phenotype (SASP) in endothelial cells (ECs), which contributes to DOX-induced inflammaging.
Ibrahim Y. Abdelgawad +4 more
doaj +1 more source
Osteoimmune senescence in aging-related bone diseases. [PDF]
Front ImmunolAging-related bone diseases are increasingly recognized as disorders in which uncoupled bone remodeling remains central but is substantially modified by immune-skeletal interactions. This review consolidates current evidence for osteoimmune senescence, a
Li H, Yang Y, Zhu H.
europepmc +2 more sources
პრეპარატების შედარებითი ანალიზი, რომლებიც აუმჯობესებენ სიცოცხლის ხარისხს და სიცოცხლის ხანგრძლივობას.
, 2023 Several classes of drugs have been introduced to cellular senescence. Senomorphics that target senescence-associated secretory phenotype and senolytics, which clear senescent cells, have been shown to attenuate ageing impacts. This article introduces the
Tkemaladze, Jaba, Kipshidze, Mariam
core +1 more source