The impacts of endothelial cell senescence on ageing-related blood-brain barrier dysfunction and the potential therapeutic strategies [PDF]
Background: Disruption of the blood-brain barrier (BBB) contributes to various agerelated neurological disorders. Brain microvascular endothelial cells (BMECs) are the most critical components of the BBB, forming a tightly sealed yet selectively ...
Ya, Jingyuan
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A novel senotherapeutic strategy with azithromycin for preventing endometriosis progression
Reproductive Biology and EndocrinologyEndometriosis is an estrogen-dependent chronic inflammatory disease, however the mechanisms underlying inflammation remain unclear. Non-hormonal drugs that can prevent endometriosis progression and resolve endometriotic infertility are urgently required. We thus focused on cellular senescence as a novel feature of endometriosis.
Reina Sonehara +11 more
openaire +3 more sources
The Emerging Field of Senotherapeutic Drugs [PDF]
Future Medicinal Chemistry, 2018 openaire +3 more sources
Chronic Use of Azithromycin Might Explain the Low Prevalence of COVID-19 in Cystic Fibrosis Patients [PDF]
, 2020 Sara, Galimberti
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Old, but gold? Not the case for the immune system when promoting systemic ageing [PDF]
, 2022 Bollini, Sveva, Guzik, Tomasz J
core +1 more source
Real-World Clinical Practice on Skin Rejuvenation Among Korean Board-Certified Dermatologists: Survey-Based Results. [PDF]
Ann DermatolOh S +14 more
europepmc +1 more source
Senolytics as Modulators of Critical Signaling Pathways: a Promising Strategy to Combat Brain Aging and Neurodegenerative Disorders. [PDF]
Mol NeurobiolSingh I, Singh AK.
europepmc +1 more source
Space radiation induces distinct senescent phenotypes: Implications for space travel. [PDF]
NPJ AgingPitcher LE +14 more
europepmc +1 more source
The geroscience hypothesis: Economic paradigms and pharmacological strategies for healthspan extension. [PDF]
J Taibah Univ Med SciAlotaibi AF +4 more
europepmc +1 more source