Results 71 to 80 of about 118,565,731 (151)
The FEBS Journal, Volume 293, Issue 10, Page 2908-2927, May 2026.The biosynthesis of bilins, tetrapyrroles essential for light harvesting and sensing, is performed by specific enzymes (FDBRs). In Galdieria sulphuraria, both phycobiliprotein types bind phycocyanobilin, despite lacking the canonical synthesizing gene PCYA. Instead, PEBA and PEBB are encoded, producing phycoerythrobilin, proposed to be later isomerized
Federica Frascogna +4 more
wiley +1 more source
Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond
Advanced Science, Volume 13, Issue 23, 23 April 2026.Therapeutic gases, including NO, CO, H2S, H2, CO2, O2, and Xe, play vital roles in cellular signaling and repair. This review highlights the emerging carriers and delivery systems that enable controlled, localized gas release for diagnostic and therapeutic applications.
Syed Muntazir Andrabi +4 more
wiley +1 more source
Journal of Biological Chemistry, 1994 This report describes for the first time the identification of four forms of biliverdin reductase including two biliverdin-IX beta reductases and two biliverdin-IX alpha reductases, designated isozymes I and II and isozymes III and IV, respectively, in human liver cytosolic fractions. The four forms of biliverdin reductase were purified to homogeneity.
T, Yamaguchi, Y, Komoda, H, Nakajima
openaire +2 more sources
Nature Communications, 2017 Biliverdin reductase (BVR) catalyses the last step in haem degradation. Here the authors present the crystal structure of cyanobacterial BVR bound to its substrate biliverdin and oxidised cofactor NADP+, which was used to propose the catalytic mechanism ...
Haruna Takao +16 more
doaj +1 more source
Heme-Derived Metabolic Signals Dictate Immune Responses
Frontiers in Immunology, 2020 Heme is one of the most abundant molecules in the body acting as the functional core of hemoglobin/myoglobin involved in the O2/CO2 carrying in the blood and tissues, redox enzymes and cytochromes in mitochondria.
Giacomo Canesin +3 more
doaj +1 more source
Ferroptotic neurodegeneration and diet: a narrative review
Alzheimer's &Dementia, Volume 22, Issue 4, April 2026.Dietary regimes and separate components have been reported to reduce ferroptosis by (1) altering iron metabolism, (2) increasing antioxidant defense, and (3) reducing lipid peroxidation. This ultimately leads to reduced ferroptosis and neurodegeneration.
Ximaine R. van der Burg +4 more
wiley +1 more source
Cancer Management and Research, 2020 Haiyan Mao,1,2 Yuan Xu,1 Zhengrong Zhang,1 Guozhuang Sun,3 Zhu Wang,1 Dawei Qiao,2 Xudong Yin,1 Siping Liu,4 Ping Bo2 1Oncology Department, The Affiliated Hospital of Yangzhou University, Yangzhou University, Yangzhou, Jiangsu Province 225000, People ...
Mao H +8 more
doaj
Journal of Cellular and Molecular Medicine, Volume 30, Issue 8, April 2026.ABSTRACT Ferroptosis and pyroptosis are two distinct forms of regulated cell death that play crucial roles in cancer, neurodegeneration, and inflammatory diseases. Ferroptosis is characterised by iron‐dependent lipid peroxidation, while pyroptosis is an inflammatory cell death mediated by gasdermin proteins.
Wei‐Yi Zhao +3 more
wiley +1 more source
Kinetic studies on biliverdin-IXalpha reductase
, 2006 THESIS 7990The species distribution of biliverdin-IXa reductase (BVR-A) has been reinvestigated. It appears increasingly likely that birds and amphibia have the potential to express an active biliverdin-IXa reductase. The full length cDNAs encoding human,
Franklin, Edward
core
Journal of Biomedical Materials Research Part A, Volume 114, Issue 3, March 2026.ABSTRACT Age‐related macular degeneration (AMD) is a leading cause of irreversible vision loss in the aging population, with no curative treatment currently available. Current therapies primarily target late‐stage symptoms and are limited by their frequent and invasive intravitreal (IVT) injections.
Amna Abdalbaqi +4 more
wiley +1 more source